Ventricular arrhythmias after cardiac resynchronization therapy: does reverse remodelling reverse risk?
نویسندگان
چکیده
منابع مشابه
Myocardial contractile reserve during exercise predicts left ventricular reverse remodelling after cardiac resynchronization therapy.
AIMS Lack of response to cardiac resynchronization therapy (CRT) may be due to the presence of significant amount of scar or fibrotic tissue at myocardial level. This study sought to investigate the potential impact of myocardial contractile reserve as assessed during exercise echocardiography on left ventricular (LV) reverse remodelling (decrease in LV end-systolic volume > or =15% after 6 mon...
متن کاملCardiac resynchronization therapy-induced left ventricular reverse remodelling is associated with reduced plasma annexin A5.
AIMS Cardiac resynchronization therapy (CRT) diminishes cardiac apoptosis and improves systolic function in heart failure (HF) patients with ventricular dyssynchrony. Plasma annexin A5 (AnxA5), a protein related to cellular damage, is associated with systolic dysfunction. We investigated whether the response to CRT is associated with plasma AnxA5. We also studied AnxA5 overexpression effects in...
متن کاملUtility of a new left ventricular asynchrony index as a predictor of reverse remodelling after cardiac resynchronization therapy.
AIMS The majority of tissue Doppler indexes proposed to predict left ventricular (LV) reverse remodelling in cardiac resynchronization therapy (CRT) reflects LV asynchrony as assessed in ejection phase. We evaluated the predictive value of a new strain-imaging parameter reflecting the total amount of time spent by 12 LV segments in contracting after aortic valve closure. METHODS AND RESULTS F...
متن کاملLeft ventricular reverse remodeling but not clinical improvement predicts long-term survival after cardiac resynchronization therapy.
BACKGROUND In patients with severe heart failure and dilated cardiomyopathy, cardiac resynchronization therapy (CRT) improves left ventricular (LV) systolic function associated with LV reverse remodeling and favorable 1-year survival. However, it is unknown whether LV reverse remodeling translates into a better long-term prognosis and what extent of reverse remodeling is clinically relevant, wh...
متن کاملPredictors of sustained ventricular arrhythmias in cardiac resynchronization therapy.
BACKGROUND Patients undergoing cardiac resynchronization therapy (CRT) are at high risk for ventricular arrhythmias (VAs), and risk stratification in this population remains poor. METHODS AND RESULTS This study followed 269 patients (left ventricular ejection fraction <35%; QRS >120 ms; New York Heart Association class III/IV) undergoing CRT with a defibrillator for 553±464 days after CRT wit...
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ژورنال
عنوان ژورنال: European Heart Journal
سال: 2015
ISSN: 0195-668X,1522-9645
DOI: 10.1093/eurheartj/ehv413